Abstract
A 70-year-old male scientist, who had returned 5 weeks earlier from Ethiopia, was admitted to the hospital with symptoms consistent with malaria. On physical examination, he had orthostatic hypotension. He was dehydrated and showed a mild clinical delirium. Abdominal examination revealed a possible spleen tip, and he had petechial lesions bilaterally below his knees. Laboratory data revealed his white blood cell count to be 4,500/mL, with 67% polymorphonuclear cells and 15% band forms. The hemoglobin level was 13.9 g/dL, and the platelet count was low, at 32,000/mL.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Aged
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Animals
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Antimalarials / therapeutic use*
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Atovaquone
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Cytochromes b / genetics
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Drug Administration Schedule
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Drug Combinations
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Ethiopia
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Humans
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Malaria, Vivax / blood
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Malaria, Vivax / diagnosis
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Malaria, Vivax / drug therapy*
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Malaria, Vivax / prevention & control*
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Male
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Naphthoquinones / therapeutic use*
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Plasmodium vivax / genetics
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Polymorphism, Genetic
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Proguanil / therapeutic use*
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Sequence Analysis, DNA / methods
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Travel*
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Treatment Failure
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United States
Substances
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Antimalarials
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Drug Combinations
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Naphthoquinones
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atovaquone, proguanil drug combination
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Cytochromes b
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Proguanil
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Atovaquone