[Tamoxifen, endometrial cancer and levonorgestrel intra-uterine device]

Gynecol Obstet Fertil. 2003 Oct;31(10):867-71. doi: 10.1016/j.gyobfe.2003.07.006.
[Article in French]

Abstract

Although the adjuvant tamoxifen benefit/risk rate is unquestionable in breast cancer treatment, the increase of endometrial cancer in chemoprevention is about to be a real problem. In the studies currently published metrorragia in the main signal. Levonogestrel intra-uterine device has not proved its efficacy for the decrease of this risk.

Publication types

  • English Abstract

MeSH terms

  • Antineoplastic Agents, Hormonal / adverse effects*
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Breast Neoplasms / drug therapy
  • Endometrial Neoplasms / chemically induced
  • Endometrial Neoplasms / prevention & control
  • Endometrium / drug effects*
  • Female
  • Humans
  • Intrauterine Devices, Medicated*
  • Levonorgestrel / administration & dosage*
  • Metrorrhagia / chemically induced
  • Metrorrhagia / prevention & control
  • Tamoxifen / adverse effects*
  • Tamoxifen / therapeutic use
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Hormonal
  • Tamoxifen
  • Levonorgestrel