Abstract
LC-MSn analysis of mycolactone toxin from extracts of Mycobacterium ulcerans has shown that minor co-metabolites, including two previously unreported, differ structurally from mycolactone only in a small portion of the polyketide side-chain.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Toxins / biosynthesis*
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Bacterial Toxins / chemistry
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Bacterial Toxins / metabolism*
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Chromatography, Liquid
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Humans
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Macrolides
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Molecular Structure
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Mycobacterium Infections, Nontuberculous / microbiology*
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Mycobacterium ulcerans / isolation & purification
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Mycobacterium ulcerans / metabolism*
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Spectrometry, Mass, Electrospray Ionization
Substances
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Bacterial Toxins
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Macrolides
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mycolactone