The experimental systemic perfused lung: histological observations in the dog

Pathologica. 1992 May-Jun;84(1091):325-9.

Abstract

An experimental model of pulmonary hypertension was obtained in the dog implanting the left main pulmonary artery in the descending thoracic aorta. The main histological lesions consisted in an increased muscularity of the pulmonary artery itself and of its lobar branches.

MeSH terms

  • Acute Disease
  • Anastomosis, Surgical
  • Animals
  • Aorta, Thoracic / surgery
  • Disease Models, Animal*
  • Dogs
  • Hemodynamics
  • Hypertension, Pulmonary / pathology*
  • Hypertrophy
  • Lung / blood supply
  • Lung / pathology*
  • Male
  • Muscle, Smooth / pathology
  • Perfusion / methods*
  • Pulmonary Artery / surgery