Using a testing-the-limits paradigm, the authors investigated the modulation (attenuation) of negative adult age differences in imagery-based memory performance as a function of professional expertise. Six older graphic designers, 6 normal older adults, 6 younger graphic design students, and 6 normal younger students participated in a 19-session program with a cued-recall variant of the Method of Loci. Older graphic designers attained higher levels of mnemonic performance than normal older adults but were not able to reach younger adults' level of performance; a perfect separation of age groups was achieved. Spatial visualization was a good predictor of mnemonic performance. Results suggest that negative adult age differences in imagery-based memory are attenuated but not eliminated by the advantages associated with criterion-relevant ability (talent) and experience.