Prognostic significance of an elevated creatine kinase in the absence of an elevated troponin I during an acute coronary syndrome

Am J Cardiol. 2003 Dec 15;92(12):1442-4. doi: 10.1016/j.amjcard.2003.08.055.

Abstract

In patients with troponin-negative acute coronary syndromes, creatine kinase (CK)-MB elevation predicts a significantly higher risk of death and major acute cardiac events compared with CK-MB negative patients. This risk is accentuated in troponin-negative, CK-MB positive patients who do not demonstrate ST elevation by electrocardiogram.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Aged
  • Biomarkers / blood
  • Coronary Disease / blood*
  • Coronary Disease / complications
  • Coronary Disease / mortality
  • Creatine Kinase / blood*
  • Female
  • Heart Failure / complications
  • Humans
  • Isoenzymes / blood*
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Patient Readmission / statistics & numerical data
  • Predictive Value of Tests
  • Prognosis
  • Syndrome
  • Troponin I / blood*

Substances

  • Biomarkers
  • Isoenzymes
  • Troponin I
  • Creatine Kinase