Abstract
To date, there is no proved medical therapy able to significantly reduce the degenerative process of biologic prosthetic aortic valves. It has recently been suggested that statins may reduce the progression of native aortic valve stenosis. We examined the effect of statin treatment on bioprosthetic aortic valve degeneration and found a beneficial effect of statins in slowing bioprosthetic degeneration.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Aortic Valve / diagnostic imaging
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Aortic Valve / surgery
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Aortic Valve Insufficiency / etiology
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Aortic Valve Insufficiency / prevention & control*
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Aortic Valve Stenosis / complications
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Aortic Valve Stenosis / prevention & control*
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Atorvastatin
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Bioprosthesis*
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Coronary Artery Bypass
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Coronary Artery Disease / complications
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Female
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Heart Valve Prosthesis*
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Heptanoic Acids / therapeutic use
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Humans
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
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Hypercholesterolemia / complications
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Male
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Pravastatin / therapeutic use
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Prosthesis Failure*
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Pyrroles / therapeutic use
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Retrospective Studies
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Simvastatin / therapeutic use
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Treatment Outcome
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Ultrasonography
Substances
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Heptanoic Acids
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Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Pyrroles
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Atorvastatin
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Simvastatin
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Pravastatin