Angiographic embolization for liver injuries: low mortality, high morbidity

J Trauma. 2003 Dec;55(6):1077-81; discussion 1081-2. doi: 10.1097/01.TA.0000100219.02085.AB.

Abstract

Objective: Angiographic embolization (AE) is a safe and effective method for controlling hemorrhage in both blunt and penetrating liver injuries. Improved survival after hepatic injuries has been documented using a multimodality approach; however, patients still have significant long-term morbidity. This study examines further the role of AE in both blunt and penetrating liver injuries and the outcomes of its use.

Methods: The medical records of 37 consecutive patients admitted from 1995 to 2002 to a Level I trauma center who underwent hepatic angiography with the intent to embolize were reviewed. Demographic and clinical information including Injury Severity Score, length of stay, mortality, intra-abdominal complications, admission physiologic variables, and the number and type of abdominal operations performed were collected.

Results: Thirty-seven patients underwent hepatic angiography and 26 patients had hepatic embolization performed. Eleven patients underwent early-AE, immediately after computed tomographic scanning, and 15 underwent late-AE, after liver-related operations or later in their hospital course. There was a 27% mortality rate overall. There were 11 liver-related complications in the 26 embolizations. Excluding the early deaths, the associated morbidity was 58%, which included hepatic necrosis, hepatic abscesses, and bile leaks.

Conclusion: There is increasing adjunctive use of AE in patients managed both operatively and nonoperatively. Intra-abdominal complications are common in these salvaged patients with severe liver injuries. Those patients that underwent early-AE received significantly fewer blood transfusions and more commonly had sterile hepatic collections. Only 26% of patients required liver-related surgery after AE. Therefore, the integration of AE as an adjunctive modality for patients with high-grade liver injuries is a safe and effective therapeutic option.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography / adverse effects
  • Angiography / methods*
  • Embolization, Therapeutic / adverse effects
  • Embolization, Therapeutic / methods*
  • Female
  • Hemorrhage / diagnostic imaging
  • Hemorrhage / etiology
  • Hemorrhage / therapy*
  • Hepatic Artery
  • Hospitals, University
  • Humans
  • Injury Severity Score
  • Length of Stay / statistics & numerical data
  • Liver / diagnostic imaging
  • Liver / injuries*
  • Male
  • Middle Aged
  • Morbidity
  • New Jersey / epidemiology
  • Predictive Value of Tests
  • Radiography, Interventional / methods*
  • Retrospective Studies
  • Survival Analysis
  • Trauma Centers
  • Treatment Outcome
  • Wounds, Nonpenetrating / complications*
  • Wounds, Nonpenetrating / mortality
  • Wounds, Penetrating / complications*
  • Wounds, Penetrating / mortality