New tetherable derivatives of myo-inositol 2,4,5- and 1,3,4-trisphosphates

J F Marecek; V A Estevez; G D Prestwich

doi:10.1016/0008-6215(92)85039-3

New tetherable derivatives of myo-inositol 2,4,5- and 1,3,4-trisphosphates

Carbohydr Res. 1992 Oct 9:234:65-73. doi: 10.1016/0008-6215(92)85039-3.

Authors

J F Marecek¹, V A Estevez, G D Prestwich

Affiliation

¹ Department of Chemistry, State University of New York, Stony Brook 11794-3400.

PMID: 1468081
DOI: 10.1016/0008-6215(92)85039-3

Abstract

(+/-)-myo-Inositol 1-(3-aminopropyl hydrogen phosphate) 3,4-bis(disodium phosphate) (5) and (+/-)-myo-inositol 2-(3-aminopropyl hydrogen phosphate) 4,5-bis(disodium phosphate) (11) have been synthesized by conventional procedures. Each derivative has been immobilized on a polymeric resin in order to give a bioaffinity matrix.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Inositol Phosphates / chemical synthesis*
Molecular Structure

Substances

Inositol Phosphates
myo-inositol 1-(3-aminopropyl hydrogen phosphate) 3,4-bisphosphate
myo-inositol 2-(3-aminopropyl hydrogen phosphate) 4,5-bisphosphate
inositol 2,4,5-trisphosphate
inositol 1,3,4-trisphosphate

Grants and funding

NS-29632/NS/NINDS NIH HHS/United States