Abstract
Analysis of T-cell subsets accumulating in the lungs of C57BL/6 mice chronically infected with Mycobacterium tuberculosis revealed that both CD4 and CD8 T-cell populations expressed a cell surface phenotype consistent with that of effector T cells and that a significant proportion of these cells were in the process of secreting gamma interferon.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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CD4-Positive T-Lymphocytes / immunology*
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CD8-Positive T-Lymphocytes / immunology*
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Chronic Disease
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Flow Cytometry
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L-Selectin / metabolism
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Lung / cytology
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Lung / immunology*
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Lymphocyte Activation
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Mice
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Mice, Inbred C57BL
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Mycobacterium tuberculosis / immunology*
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Phenotype
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T-Lymphocytes, Regulatory / immunology*
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Tuberculosis, Pulmonary / immunology