Synovial sarcoma: a rare tumor of larynx

Pathol Oncol Res. 2003;9(4):242-5. doi: 10.1007/BF02893385. Epub 2003 Dec 22.

Abstract

Synovial sarcoma is a soft tissue sarcoma of unknown histogenesis and occurs predominantly in the lower extremities of young adults. The head and neck is a relative rare location. There are about 10 cases with laryngeal localization in the literature. We present a 24 year-old male with an endolaryngeal mass. Incisional biopsy and the hemilaryngectomy material revealed a biphasic synovial sarcoma. One year later a local recurrence occurred. Tumor excision and neck dissection were performed. Radiotherapy was added. Six months later lung metastases was discovered on thoracic CT. The patient received chemotherapy for 6 courses. The metastases responded well to chemotherapy and the patient is now alive without tumor on radiological and clinical examination after 3.5 years of follow-up.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Combined Modality Therapy
  • Humans
  • Immunohistochemistry
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / therapy
  • Laryngectomy
  • Lung Neoplasms / secondary
  • Lung Neoplasms / therapy
  • Male
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / therapy
  • Radiotherapy
  • Sarcoma, Synovial / secondary*
  • Sarcoma, Synovial / therapy