Abstract
In vitro activities of DA-7867, a novel oxazolidinone, were compared to those of linezolid and commonly used antimicrobials. DA-7867 had the lowest MIC for 90% of the aerobic gram-positive bacterial strains tested, </=0.25 micro g/ml, and it was more potent than linezolid.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetamides / pharmacology
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Anti-Infective Agents / pharmacology*
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Bacteria, Aerobic / drug effects*
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Bacteria, Anaerobic / drug effects*
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Bacterial Infections / microbiology*
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Bacteroides / drug effects
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Drug Resistance, Bacterial
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Enterococcus faecalis / drug effects
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Enterococcus faecium / drug effects
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Gram-Negative Bacteria / drug effects
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Linezolid
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Methicillin Resistance
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Microbial Sensitivity Tests
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Oxazolidinones / pharmacology*
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Staphylococcus aureus / drug effects
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Vancomycin Resistance
Substances
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Acetamides
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Anti-Infective Agents
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DA-7867
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Oxazolidinones
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Linezolid