Angioplasty and stenting for high-grade internal carotid artery stenosis: safety study in 39 selected patients

Cerebrovasc Dis. 2004;17(2-3):160-5. doi: 10.1159/000075785. Epub 2003 Dec 23.

Abstract

Background: Carotid angioplasty and stenting (CAS) is sometimes used as an alternative to surgery, despite the lack of evidence for its safety and efficacy.

Method: Over a 33-month period, 39 consecutive patients with a stenosis >/=70% underwent CAS (4 in a randomized trial and 35 because of contra-indications for surgery).

Results: In 5 patients (13%; 95% CI: 3-23), a major complication occurred (3 disabling ischaemic strokes, 1 myocardial infarction, 1 acute interstitial nephropathy). In 7 patients (18%; 95% CI: 6-30), a minor complication occurred (5 transient ischaemic attacks, 1 transient confusional state, 1 non-disabling ischaemic stroke).

Conclusion: CAS cannot be considered as a routine procedure and should be restricted to high-risk patients unfit for surgery.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angioplasty*
  • Carotid Artery, Internal / surgery*
  • Carotid Stenosis / mortality
  • Carotid Stenosis / surgery*
  • Female
  • Humans
  • Ischemic Attack, Transient / mortality
  • Male
  • Middle Aged
  • Postoperative Complications / mortality
  • Stents*
  • Stroke / mortality
  • Treatment Outcome