Diffusion tensor MR imaging visualizes the altered hemispheric fiber connection in callosal dysgenesis

AJNR Am J Neuroradiol. 2004 Jan;25(1):25-8.

Abstract

We report three cases of callosal dysgenesis that were evaluated by diffusion tensor imaging and fiber tractography. In partial agenesis of corpus callosum, fiber tracts from all regions of brain converged to a partially developed small genu portion and connected to the contralateral side. In complete callosal agenesis, fibers from the hemispheres failed to cross the midline and formed thick bundles running anteroposteriorly (eg, Probst bundle). The thickness of the anterior commissure was enlarged or smaller than normal brain, and other white matter tracts were not markedly different from normal brain tissue.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / diagnostic imaging
  • Abnormalities, Multiple / pathology
  • Agenesis of Corpus Callosum*
  • Anisotropy
  • Cerebral Ventricles / pathology
  • Corpus Callosum / diagnostic imaging*
  • Diffusion Magnetic Resonance Imaging*
  • Humans
  • Infant
  • Infant Welfare
  • Infant, Newborn
  • Male
  • Nerve Fibers, Myelinated / diagnostic imaging*
  • Nerve Fibers, Myelinated / pathology*
  • Radiographic Image Enhancement