Carbofuran-induced acute pancreatitis

JOP. 2004 Jan;5(1):44-7.

Abstract

Context: Carbamate insecticides are widely used in commercial agriculture and home gardening. A serious side effect of organophosphate and carbamate intoxication is the development of acute pancreatitis.

Case report: A 36-year-old Caucasian woman was admitted to our hospital with cholinergic crisis and pancreatitis soon after the ingestion of a carbamate insecticide (carbofuran). An abdominal CT scan disclosed pancreatic necrosis with intrapancreatic fluid collection, consistent with the development of a pancreatic pseudocyst in a subsequent CT scan. No predisposing factor for pancreatitis was evident. Pseudocholinesterase levels returned to normal 7 days later and the patient was discharged in good physical condition one month after admission.

Discussion: Although acute pancreatitis is not infrequent after organophosphate intoxication, it is quite rare after carbamate ingestion and has not been previously reported after carbofuran intoxication.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Carbofuran / poisoning*
  • Female
  • Humans
  • Insecticides / poisoning*
  • Pancreatitis / chemically induced*
  • Pancreatitis / diagnosis
  • Pancreatitis / diagnostic imaging
  • Tomography, X-Ray Computed

Substances

  • Insecticides
  • Carbofuran