The crystal structure of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveals a novel architecture for the bifunctional enzyme

J Eukaryot Microbiol. 2003:50 Suppl:555-6. doi: 10.1111/j.1550-7408.2003.tb00627.x.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Line
  • Cryptosporidium / enzymology*
  • Crystallography, X-Ray
  • Models, Molecular
  • Multienzyme Complexes / chemistry*
  • Protein Conformation
  • Tetrahydrofolate Dehydrogenase / chemistry*
  • Thymidylate Synthase / chemistry*

Substances

  • Multienzyme Complexes
  • thymidylate synthase-dihydrofolate reductase
  • Tetrahydrofolate Dehydrogenase
  • Thymidylate Synthase