Polyarteritis nodosa and hypertrophic obstructive cardiomyopathy. A true association?

Clin Rheumatol. 2004 Feb;23(1):57-8. doi: 10.1007/s10067-003-0798-y. Epub 2003 Nov 7.

Abstract

A 60-year-old man with polyarteritis nodosa under treatment presented with syncope. Echocardiography demonstrated hypertrophic obstructive cardiomyopathy; coronary arteriography revealed normal findings, and Holter monitor showed episodes of non-sustained ventricular tachycardia. This is the first report of hypertrophic obstructive cardiomyopathy developing in a patient with polyarteritis nodosa. Further studies should examine whether a true association exists.

Publication types

  • Case Reports

MeSH terms

  • Amiodarone / therapeutic use
  • Anti-Arrhythmia Agents / therapeutic use
  • Cardiomyopathy, Hypertrophic / complications*
  • Cardiomyopathy, Hypertrophic / drug therapy
  • Cardiomyopathy, Hypertrophic / pathology
  • Cyclophosphamide / therapeutic use
  • Drug Therapy, Combination
  • Echocardiography
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Polyarteritis Nodosa / complications*
  • Polyarteritis Nodosa / drug therapy
  • Polyarteritis Nodosa / pathology
  • Treatment Outcome
  • Verapamil / therapeutic use

Substances

  • Anti-Arrhythmia Agents
  • Immunosuppressive Agents
  • Cyclophosphamide
  • Verapamil
  • Amiodarone
  • Methylprednisolone