Abstract
We report the case of a 46-year-old woman presenting cutaneous lesions similar to those of pityriasis rubra pilaris, characterized by diffuse scaling erythroderma and palmoplantar keratoderma; skin biopsy showed follicular hyperkeratosis with a perivascular lymphocytic infiltrate. One year later she developed an inflammatory myopathy; on the basis of clinical features, a diagnosis of dermatomyositis was made. Treatment with prednisone and hydroxychloroquine led to complete control of the cutaneous and muscular involvement, which was maintained during prednisone tapering.
MeSH terms
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Anti-Inflammatory Agents / therapeutic use
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Dermatologic Agents / therapeutic use
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Dermatomyositis / complications*
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Dermatomyositis / drug therapy
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Dermatomyositis / pathology
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Drug Therapy, Combination
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Female
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Humans
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Hydroxychloroquine / therapeutic use
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Keratoderma, Palmoplantar / etiology
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Keratoderma, Palmoplantar / pathology
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Middle Aged
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Pityriasis Rubra Pilaris / drug therapy
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Pityriasis Rubra Pilaris / etiology*
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Pityriasis Rubra Pilaris / pathology
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Prednisone / therapeutic use
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Treatment Outcome
Substances
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Anti-Inflammatory Agents
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Dermatologic Agents
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Hydroxychloroquine
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Prednisone