Deficiency of the circulating insulin-like growth factor system associated with inactivation of the acid-labile subunit gene

N Engl J Med. 2004 Feb 5;350(6):570-7. doi: 10.1056/NEJMoa013100.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Carrier Proteins / genetics*
  • Glycoproteins / deficiency*
  • Glycoproteins / genetics*
  • Gonadal Steroid Hormones / blood
  • Growth Disorders / blood
  • Growth Disorders / drug therapy
  • Growth Disorders / genetics*
  • Human Growth Hormone / blood
  • Human Growth Hormone / metabolism
  • Human Growth Hormone / therapeutic use
  • Humans
  • Insulin-Like Growth Factor Binding Protein 3 / deficiency*
  • Male
  • Puberty, Delayed / blood
  • Puberty, Delayed / genetics*

Substances

  • Carrier Proteins
  • Glycoproteins
  • Gonadal Steroid Hormones
  • Insulin-Like Growth Factor Binding Protein 3
  • insulin-like growth factor binding protein, acid labile subunit
  • Human Growth Hormone