On a 3-D representation of DNA primary sequences

Comb Chem High Throughput Screen. 2004 Feb;7(1):23-7. doi: 10.2174/138620704772884797.

Abstract

We introduce a graphical representation of DNA primary sequences by taking four special vectors in a 3-D space to represent the four nucleic acid bases in DNA sequences, so that a DNA primary sequence is denoted in a 3-D space by a successive vector sequence which is a directed walk on the space. It is demonstrated that this representation has no overlap and intersection and allows numerical characterization.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Base Sequence
  • Computer Graphics
  • DNA / chemistry*
  • Models, Molecular*
  • Molecular Sequence Data
  • Sequence Analysis, DNA

Substances

  • DNA