A case of Cotard syndrome: (123)I-IBZM SPECT imaging of striatal D(2) receptor binding

Sergio De Risio; Giuseppe De Rossi; Marco Sarchiapone; Giovanni Camardese; Vladimir Carli; Chiara Cuomo; Maria Antonietta Satta; Daniela Di Giuda

doi:10.1016/j.pscychresns.2003.01.001

A case of Cotard syndrome: (123)I-IBZM SPECT imaging of striatal D(2) receptor binding

Psychiatry Res. 2004 Jan 15;130(1):109-12. doi: 10.1016/j.pscychresns.2003.01.001.

Authors

Sergio De Risio¹, Giuseppe De Rossi, Marco Sarchiapone, Giovanni Camardese, Vladimir Carli, Chiara Cuomo, Maria Antonietta Satta, Daniela Di Giuda

Affiliation

¹ Institute of Psychiatry, Catholic University of Sacred Heart, Largo Gemelli 8, Rome 00168, Italy.

PMID: 14972373
DOI: 10.1016/j.pscychresns.2003.01.001

Abstract

A case of 'dèlire de nègation' that suddenly appeared in a 43-year-old male is presented. No alteration in regional cerebral blood, as measured by (99m)Tc-HMPAO-SPECT, was found, but (123)I-IBZM-SPECT analysis showed reduced striatal D(2) receptor binding that further decreased after treatment.

Publication types

Case Reports

MeSH terms

Adolescent
Adult
Benzamides*
Binding, Competitive
Contrast Media
Corpus Striatum / metabolism*
Delusions / diagnosis*
Humans
Male
Pyrrolidines*
Receptors, Dopamine D2 / metabolism*
Syndrome
Tomography, Emission-Computed, Single-Photon*

Substances

Benzamides
Contrast Media
Pyrrolidines
Receptors, Dopamine D2
3-iodo-2-hydroxy-6-methoxy-N-((1-ethyl-2-pyrrolidinyl)methyl)benzamide