We report the case of a pregnant woman presenting with Guillain-Barré syndrome in which her neurologic status worsened immediately after delivery under epidural analgesia. We believe that the anesthetic technique may have played a role in the disease progression. Because of this potential association, the risks of worsening neurologic status after regional anesthesia and alternative analgesia options should be discussed with the parturient.
Implications: Because of the potential interaction between regional anesthesia and Guillain-Barré syndrome in pregnant women, the risks of worsening neurologic status and alternative analgesia options should be discussed with the parturient.