Abstract
This paper introduces the first integrated algorithm designed to discover novel motifs in heterogeneous sequence data, which is comprised of coregulated genes from a single genome together with the orthologs of these genes from other genomes. Results are presented for regulons in yeasts, worms, and mammals.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Algorithms*
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Animals
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Binding Sites / genetics
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Caenorhabditis elegans / genetics
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Computational Biology*
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Genes, Helminth
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Genes, Regulator
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Genomics / statistics & numerical data
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Models, Genetic
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Sequence Analysis, DNA / statistics & numerical data*