Molecular imaging for pediatric lung diseases

Pediatr Pulmonol. 2004 Apr;37(4):286-96. doi: 10.1002/ppul.20024.

Abstract

Molecular imaging is a rapidly developing multidisciplinary field that combines advances in contrast agent development, instrumentation, and molecular/cell biology to follow cellular and sub-cellular events in intact organisms. Platforms for molecular imaging include radionuclide-based methods, optical methods, and magnetic resonance. To date, molecular imaging studies of the lungs have been used to monitor the effectiveness of gene transfer, neutrophilic inflammation, and cell trafficking. Eventually, the goal will be to translate these new techniques to clinical settings such as cystic fibrosis.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Diagnostic Imaging / methods*
  • Fluorodeoxyglucose F18
  • Gene Expression
  • Genes, Reporter
  • Humans
  • Inflammation / pathology
  • Lung Diseases / diagnosis*
  • Lung Diseases / genetics
  • Radiopharmaceuticals

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18