Current options in prosthetic vascular graft infection: comparative analysis of 63 consecutive cases

Langenbecks Arch Surg. 2004 Aug;389(4):272-7. doi: 10.1007/s00423-004-0458-y. Epub 2004 Mar 16.

Abstract

Purpose: The study was conducted to compare the results of two different techniques of vascular reconstruction in patients after the removal of infected vascular prostheses.

Methods: Sixty-three patients with vascular prostheses infections underwent treatment. Either the infected fragments or the entire prosthesis was removed in all of the patients. Extra-anatomical grafts were implanted in 19 cases. Cryopreserved allogenic arterial grafts were applied for reconstruction in 44 patients.

Results: In a 19-patient group with extra-anatomical grafts, two patients died (10.5%). In seven patients (36.8%) relapse symptoms of infection appeared. Primary and secondary patencies of the grafts after 3 years were 31.6% and 52.6% respectively. In a group of 44 patients with allogenic grafts no recurrence of infection was observed. Six patients died (13.6%). Primary and secondary patencies after 3 years were 63.6% and 81.8% respectively.

Conclusions: The results reveal the benefits of the allogenic arterial grafts in revascularization in patients with major vascular prostheses infections. The differences in secondary patencies of the implanted allogenic grafts indicate the necessity of an early selection of patients for the complete removal of the infected prosthesis, during a time when patients are in general good health.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bacterial Infections / epidemiology*
  • Bacterial Infections / microbiology*
  • Blood Vessel Prosthesis Implantation / methods*
  • Blood Vessel Prosthesis*
  • Female
  • Graft Survival
  • Humans
  • Male
  • Middle Aged
  • Prosthesis-Related Infections / epidemiology*
  • Prosthesis-Related Infections / microbiology*
  • Transplantation, Homologous
  • Treatment Outcome
  • Vascular Patency