Teaching tired T cells to fight HIV: time to test IL-15 for immunotherapy?

Trends Immunol. 2004 Mar;25(3):121-5. doi: 10.1016/j.it.2004.01.002.
No abstract available

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic
  • CD8-Positive T-Lymphocytes / drug effects
  • CD8-Positive T-Lymphocytes / immunology
  • Cytokines / physiology
  • Drug Evaluation, Preclinical
  • HIV / drug effects
  • HIV / physiology
  • HIV Infections / immunology
  • HIV Infections / therapy*
  • Humans
  • Immunologic Memory / drug effects
  • Immunotherapy*
  • Interleukin-15 / biosynthesis
  • Interleukin-15 / deficiency
  • Interleukin-15 / pharmacology
  • Interleukin-15 / therapeutic use*
  • Killer Cells, Natural / immunology
  • Lymphocytes / metabolism
  • T-Lymphocyte Subsets / drug effects*
  • T-Lymphocyte Subsets / immunology
  • Virus Replication / drug effects

Substances

  • Adjuvants, Immunologic
  • Cytokines
  • Interleukin-15