[Pediatric renal transplantation from young children donors (aged < or = 6 years). Complications and functional clinical course]

Actas Urol Esp. 2004 Jan;28(1):40-8. doi: 10.1016/s0210-4806(04)73034-x.
[Article in Spanish]

Abstract

Goals: To evaluate functional results and complications in a group of pediatric patients who received kidney transplants from donors aged 6 years or less.

Material & methods: Thirty-four consecutive renal transplants were reviewed. Of 34 patients, 19 (55.8%) received kidneys from donors aged below 3 years (Group A) and 15 (44.2%) from donors aged 3-6 years (Group B). Long-term functional patient and graft survival results along with complications were compared in both groups.

Results: Seven patients in group A (36.7%) had vascular complications, in comparison to 3 in group B (20%, p<0.05). Kidneys preserved in Eurocollins (EC) solution had more vascular complications (35.3%) in comparison to University of Wisconsin (UW) solution kidneys (23.5%, p<0.05). Ten-year graft survival rate in group A was significantly lower in comparison to group B (35.5% vs 58.6%, p<0.05). In relation to preservation solution type used, 10-year graft survival rate was also significantly better in UW group (26.8% vs 63%, p<0.001).

Conclusions: The exclusion of donors younger than 3 years and the utilization of optimal preservation solutions produces a decrease in figures of vascular complications and a significant improvement in graft survival rates.

Publication types

  • English Abstract

MeSH terms

  • Actuarial Analysis
  • Age Factors
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Kidney Transplantation* / adverse effects
  • Kidney Transplantation* / physiology
  • Postoperative Complications / epidemiology
  • Survival Rate
  • Tissue Donors*