Management of central diabetes insipidus with oral desmopressin in a premature neonate

J Pediatr Endocrinol Metab. 2004 Feb;17(2):227-30. doi: 10.1515/jpem.2004.17.2.227.

Abstract

The effect of oral administration of desmopressin (DDAVP) solution was investigated in a very low birth weight premature infant with central diabetes insipidus that was associated with grade four germinal matrix hemorrhage. As an alternative to the nasal route, long-term successful management resulting in favorable growth and development during infancy was achieved using the oral route.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Cerebral Hemorrhage, Traumatic / complications
  • Cerebral Hemorrhage, Traumatic / diagnostic imaging
  • Cerebral Ventriculography
  • Deamino Arginine Vasopressin / administration & dosage
  • Deamino Arginine Vasopressin / therapeutic use*
  • Diabetes Insipidus / drug therapy*
  • Diabetes Insipidus / etiology
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / therapeutic use*
  • Infant, Newborn
  • Infant, Premature / physiology*
  • Infant, Very Low Birth Weight
  • Male
  • Tomography, X-Ray Computed
  • Weight Gain / drug effects

Substances

  • Hypoglycemic Agents
  • Deamino Arginine Vasopressin