Abstract
A new compound, nigeglanine (1), and its new artificial derivative (1a), were isolated from the seeds of Nigella glandulifera, together with a known aporphine alkaloid, fuzitine (2). Their structures were established by spectral analysis, including two-dimensional (2D)-NMR spectroscopy. Nigeglanine (1) is the third natural product determined to contain an indazole nucleus.
MeSH terms
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Alkaloids / chemistry*
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Alkaloids / isolation & purification
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Heterocyclic Compounds, 3-Ring / chemistry*
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Heterocyclic Compounds, 3-Ring / isolation & purification
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Indazoles / chemistry*
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Indazoles / isolation & purification
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Nigella / chemistry*
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Seeds / chemistry
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Spectrometry, Mass, Electrospray Ionization
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Spectrophotometry, Ultraviolet
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Spectroscopy, Fourier Transform Infrared
Substances
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Alkaloids
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Heterocyclic Compounds, 3-Ring
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Indazoles
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nigeglanine