PedSplit: pedigree management for stratified analysis

M B Lanktree; L VanderBeek; F M Macciardi; J L Kennedy

doi:10.1093/bioinformatics/bth224

PedSplit: pedigree management for stratified analysis

Bioinformatics. 2004 Sep 22;20(14):2315-6. doi: 10.1093/bioinformatics/bth224. Epub 2004 Apr 1.

Authors

M B Lanktree¹, L VanderBeek, F M Macciardi, J L Kennedy

Affiliation

¹ Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, Toronto M5T 1R8, Canada.

PMID: 15059823
DOI: 10.1093/bioinformatics/bth224

Abstract

Summary: PedSplit facilitates pedigree management for gene-gene interaction and sex specific tests for increased homogeneity within subgroups. PedSplit also provides a simple approach for calculating haplotype relative risk and generating internal 'controls'.

Availability: Executables, C++ source code and documentation for PedSplit can be downloaded from http://www.pharmacogenetics.ca in the links and software section.

MeSH terms

Algorithms
Chromosome Mapping / methods*
DNA Mutational Analysis / methods*
Gene Frequency / genetics
Genetic Predisposition to Disease / genetics*
Genetic Testing / methods*
Genetic Variation / genetics
Haplotypes / genetics
Internet
Linkage Disequilibrium / genetics
Pedigree*
Risk Assessment / methods*
Risk Factors
Sex Factors
Software*