Establishment of an active laboratory-based surveillance for bacterial meningitis in Croatia and molecular characterization of Neisseria meningitidis isolates causing meningococcal disease that were collected in the year 2000, the first year of activity

A Boras; T Jeren; C T Sacchi; S Schmink; D Bozinovic; B Barsic; N E Rosenstein; T Popovic

doi:10.1128/JCM.42.4.1803-1806.2004

Establishment of an active laboratory-based surveillance for bacterial meningitis in Croatia and molecular characterization of Neisseria meningitidis isolates causing meningococcal disease that were collected in the year 2000, the first year of activity

J Clin Microbiol. 2004 Apr;42(4):1803-6. doi: 10.1128/JCM.42.4.1803-1806.2004.

Authors

A Boras¹, T Jeren, C T Sacchi, S Schmink, D Bozinovic, B Barsic, N E Rosenstein, T Popovic

Affiliation

¹ University Hospital for Infectious Diseases, Zagreb, Croatia. [email protected]

Abstract

In 2000, 23 Neisseria meningitidis (meningococcal [Men]) isolates were collected in Croatia through an active laboratory-based surveillance for bacterial meningitis (17 Men serogroup B [MenB], 4 MenC, 1 MenW135, and 1 nongroupable isolate). Molecular characterization revealed a substantial level of diversity with only six isolates belonging to electrophoretic type 5 (ET-5) and ET-37 hypervirulent complexes.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Anti-Bacterial Agents / pharmacology
Croatia / epidemiology
Electrophoresis, Gel, Pulsed-Field
Humans
Laboratories*
Meningitis, Meningococcal / epidemiology*
Meningitis, Meningococcal / microbiology
Microbial Sensitivity Tests
Molecular Epidemiology*
Neisseria meningitidis / classification*
Neisseria meningitidis / drug effects
Neisseria meningitidis / genetics
Neisseria meningitidis / isolation & purification
Population Surveillance*
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA
Serotyping

Substances

Anti-Bacterial Agents
RNA, Ribosomal, 16S