Early visual cortex organization in autism: an fMRI study

Neuroreport. 2004 Feb 9;15(2):267-70. doi: 10.1097/00001756-200402090-00011.

Abstract

Autism is a neurodevelopmental disorder characterized by preserved visual abilities as well as a special profile for visual cognition. We examined the visual cortex of high-ability individuals with autism in order to assess whether the presence of abnormalities at the primary sensory level in autism could be the basis of their unusual pattern of visual cognitive abilities. We found that the early sensory visual areas are normally organized in individuals with autism, with a normal ratio between central versus peripheral visual field representation. We conclude that the differences observed in the visual capacities of individuals with autism are likely to arise from higher-level cognitive areas and functions, and are the result of top-down processes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Attention / physiology
  • Autistic Disorder / pathology
  • Autistic Disorder / physiopathology*
  • Brain Mapping
  • Cerebral Cortex / abnormalities
  • Cerebral Cortex / growth & development
  • Cerebral Cortex / physiopathology
  • Cognition / physiology
  • Functional Laterality / physiology
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neural Pathways / abnormalities
  • Neural Pathways / growth & development
  • Neural Pathways / physiopathology
  • Photic Stimulation
  • Reference Values
  • Visual Cortex / abnormalities
  • Visual Cortex / growth & development
  • Visual Cortex / physiopathology*
  • Visual Fields / physiology
  • Visual Perception / physiology*