Brain metastases in hepatoblastoma

Pediatr Neurol. 2004 Apr;30(4):295-7. doi: 10.1016/j.pediatrneurol.2003.10.014.

Abstract

Brain metastases from hepatoblastomas are rare. We report a 2-year-old male who developed multiple hemorrhagic intracranial metastases. Previous reports indicate that brain metastases are an almost uniformly fatal complication of hepatoblastoma, although one long-term survivor has been described. In a child with known hepatoblastoma, the development of neurologic signs or symptoms should lead to the performance of a brain imaging study to exclude the possibility of intracranial extension of the disease.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / pathology
  • Brain Neoplasms / secondary*
  • Cerebral Hemorrhage / diagnosis
  • Cerebral Hemorrhage / etiology
  • Cerebral Hemorrhage / pathology
  • Child, Preschool
  • Diagnosis, Differential
  • Disease Progression
  • Fatal Outcome
  • Follow-Up Studies
  • Hepatoblastoma / diagnosis
  • Hepatoblastoma / pathology
  • Hepatoblastoma / secondary*
  • Humans
  • Infant
  • Liver / pathology
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / pathology
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / pathology
  • Lung Neoplasms / secondary
  • Male
  • Neoplasm Staging
  • Occipital Lobe / pathology
  • Parietal Lobe / pathology
  • Tomography, X-Ray Computed