Necrobiotic xanthogranuloma associated with myeloma

J Eur Acad Dermatol Venereol. 2004 May;18(3):328-31. doi: 10.1111/j.1468-3083.2004.00906.x.

Abstract

We observed a 73-year-old man with necrobiotic xanthogranuloma (NXG) on the eyelids and concurrent multiple myeloma. The treatment was surgery followed by administration of melphalan. No relapse was seen in 19 months of follow-up. We consider that surgical removal of xanthogranuloma is an advisable rapid treatment that involves fewer side-effects than other treatments.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy, Needle
  • Blood Chemical Analysis
  • Follow-Up Studies
  • Granuloma Annulare / complications
  • Granuloma Annulare / drug therapy
  • Granuloma Annulare / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Melphalan / therapeutic use
  • Multiple Myeloma / complications
  • Multiple Myeloma / drug therapy
  • Multiple Myeloma / pathology*
  • Rare Diseases
  • Risk Assessment
  • Treatment Outcome
  • Xanthomatosis / complications
  • Xanthomatosis / drug therapy
  • Xanthomatosis / pathology*

Substances

  • Melphalan