New sesterterpenes from the Antarctic sponge Suberites sp

J Nat Prod. 2004 Apr;67(4):672-4. doi: 10.1021/np030342t.

Abstract

Suberitenones C and D and suberiphenol, three new sesterterpenes of the suberitane class, were isolated from the sponge Suberites sp. collected from Antarctica. The structures of these compounds were determined on the basis of combined spectral and chemical analyses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacillus subtilis / drug effects
  • Candida albicans / drug effects
  • Drug Screening Assays, Antitumor
  • Escherichia coli / drug effects
  • Humans
  • Inhibitory Concentration 50
  • K562 Cells
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Oceans and Seas
  • Porifera / chemistry*
  • Sesterterpenes
  • Staphylococcus aureus / drug effects
  • Streptococcus / drug effects
  • Terpenes / chemistry
  • Terpenes / isolation & purification*
  • Terpenes / pharmacology
  • Tumor Cells, Cultured

Substances

  • Sesterterpenes
  • Terpenes
  • suberiphenol
  • suberitenone C
  • suberitenone D