Histological findings in "incidental" intraoperative pancreas allograft biopsies

Transplant Proc. 2004 Apr;36(3):780-1. doi: 10.1016/j.transproceed.2004.03.036.

Abstract

Thirty intraoperative needle core biopsies of well-functioning pancreas allografts were performed from 2 days to 7 years posttransplantation (mean 15.4 months). Most samples (83.3%) lacked significant inflammation or fibrosis. The five patients who showed features of ongoing low-grade acute rejection experienced premature graft losses due to chronic rejection. There were no complications related to the intraoperative biopsy itself.

MeSH terms

  • Adult
  • Biopsy, Needle*
  • Female
  • Fibrosis
  • Graft Rejection / pathology*
  • Humans
  • Incidental Findings*
  • Inflammation
  • Laparotomy
  • Male
  • Middle Aged
  • Monitoring, Intraoperative*
  • Pancreas Transplantation / pathology*
  • Transplantation, Homologous / pathology