Abstract
We present a case of primary antiphospholipid syndrome with acute renal failure and alveolar haemorrhage. He was successfully treated with cyclophosphamide, corticosteroids and plasma exchange. Patients with antiphospholipid syndrome may develop a broad spectrum of pulmonary disease. Pulmonary thromboembolism and pulmonary hypertension are the most common complications, but alveolar haemorrhage have also been reported. Other causes need to be excluded. Despite favourable outcome of many patients with association of plasma exchange, immunosuppressive drugs and anticoagulant therapy, definite conclusions about the best therapeutic regimen could not be draw.
Publication types
-
Case Reports
-
English Abstract
MeSH terms
-
Acute Kidney Injury / etiology*
-
Acute Kidney Injury / therapy
-
Adrenal Cortex Hormones / therapeutic use
-
Adult
-
Antibodies, Anticardiolipin / blood*
-
Anticoagulants / adverse effects
-
Anticoagulants / therapeutic use
-
Antiphospholipid Syndrome / complications*
-
Antiphospholipid Syndrome / drug therapy
-
Antiphospholipid Syndrome / immunology
-
Antiphospholipid Syndrome / therapy
-
Combined Modality Therapy
-
Cyclophosphamide / therapeutic use
-
Drug Therapy, Combination
-
Hemorrhage / chemically induced
-
Hemorrhage / etiology*
-
Heparin / adverse effects
-
Heparin / therapeutic use
-
Humans
-
Immunosuppressive Agents / therapeutic use
-
Intracranial Thrombosis / drug therapy
-
Intracranial Thrombosis / etiology
-
Lung Diseases / chemically induced
-
Lung Diseases / etiology*
-
Lung Diseases / therapy
-
Male
-
Plasma Exchange
-
Recurrence
-
Renal Dialysis
-
Respiration, Artificial
-
Syndrome
Substances
-
Adrenal Cortex Hormones
-
Antibodies, Anticardiolipin
-
Anticoagulants
-
Immunosuppressive Agents
-
Cyclophosphamide
-
Heparin