Serum acute phase response (APR)-related proteome of loach to trauma

Yajun Wu; Sanying Wang; Xuanxian Peng

doi:10.1016/j.fsi.2003.06.003

Serum acute phase response (APR)-related proteome of loach to trauma

Fish Shellfish Immunol. 2004 Mar;16(3):381-9. doi: 10.1016/j.fsi.2003.06.003.

Authors

Yajun Wu¹, Sanying Wang, Xuanxian Peng

Affiliation

¹ Center for Proteomics, The Key Laboratory of Education Ministry for Cell Biology and Tumor Cell Engineering, Department of Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, China.

PMID: 15123305
DOI: 10.1016/j.fsi.2003.06.003

Abstract

Proteome analysis by two-dimensional polyacrylamide gel electrophoresis (2-DE PAGE) together with mass spectrometry was applied to screen acute phase response (APR)-related proteins in serum from loach following injury. Six APR-related proteins were identified, in which apolipoprotein, cathepsin, C-reactive protein (CRP) were known APP, while signal recognition protein (SRP), gastrin 71 and parvalbumin were new APR-related proteins.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Acute-Phase Proteins / immunology
Acute-Phase Proteins / isolation & purification*
Animals
Apolipoproteins
Blood Protein Electrophoresis
C-Reactive Protein
Cathepsins
Cypriniformes / immunology*
Cypriniformes / injuries*
Electrophoresis, Polyacrylamide Gel
Gastrins
Mass Spectrometry
Parvalbumins
Protein Precursors
Signal Recognition Particle

Substances

Acute-Phase Proteins
Apolipoproteins
Gastrins
Parvalbumins
Protein Precursors
Signal Recognition Particle
big gastrin
C-Reactive Protein
Cathepsins