Abstract
Human papillomavirus type 16 (HPV-16) viral load in cervicovaginal lavage samples collected from 66 human immunodeficiency virus-seropositive women was inversely correlated with blood CD4 count (P = 0.002). HPV-16 viral load was 81-fold higher in women with cervical smears suggestive of high-grade lesions (median, 4,425,883 copies/ micro g of DNA) than in women with normal smears (median, 54,576), controlling for age (P = 0.006).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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Case-Control Studies
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DNA Primers / genetics
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DNA, Viral / genetics
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DNA, Viral / isolation & purification
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Female
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HIV Seropositivity / complications*
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HIV Seropositivity / virology*
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Humans
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Papillomaviridae / classification
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Papillomaviridae / genetics
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Papillomaviridae / isolation & purification*
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Papillomavirus Infections / complications*
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Papillomavirus Infections / pathology
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Papillomavirus Infections / virology*
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Uterine Cervical Dysplasia / complications*
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Uterine Cervical Dysplasia / pathology
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Uterine Cervical Dysplasia / virology*
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Uterine Cervical Neoplasms / complications*
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Uterine Cervical Neoplasms / virology*
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Viral Load