Outbreak of Burkholderia cepacia bacteremia in a pediatric hospital due to contamination of lipid emulsion stoppers

J Clin Microbiol. 2004 May;42(5):2227-30. doi: 10.1128/JCM.42.5.2227-2230.2004.

Abstract

We describe a 7-month outbreak of nosocomial Burkholderia cepacia bacteremia involving eight children in a pediatric hospital and the results of epidemiological investigations. A B. cepacia strain genotypically identical to the blood isolates was recovered from the upper surface of capped rubber stoppers of bottles of a commercial lipid emulsion used for parenteral nutrition.

MeSH terms

  • Bacteremia / epidemiology*
  • Bacteremia / microbiology
  • Burkholderia Infections / epidemiology*
  • Burkholderia Infections / microbiology
  • Burkholderia cepacia* / classification
  • Burkholderia cepacia* / genetics
  • Burkholderia cepacia* / isolation & purification
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Disease Outbreaks*
  • Emulsions
  • Equipment Contamination*
  • Humans
  • Infant
  • Infant, Newborn
  • Lipids
  • Parenteral Nutrition / adverse effects
  • Parenteral Nutrition / instrumentation
  • Paris / epidemiology
  • Ribotyping

Substances

  • Emulsions
  • Lipids