SCA2 presenting as levodopa-responsive parkinsonism in a young patient from the United Kingdom: a case report

Mov Disord. 2004 May;19(5):593-5. doi: 10.1002/mds.10715.

Abstract

We report on a young woman from the United Kingdom with L-dopa-responsive parkinsonism with a trinucleotide repeat expansion in her spinocerebellar ataxia 2 (SCA2) gene. The case further extends the phenotype of SCA2 and emphasizes the importance of SCA screening in young-onset parkinsonism, irrespective of ethnic origin.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alleles
  • Antiparkinson Agents / therapeutic use*
  • Ataxins
  • Female
  • Humans
  • Levodopa / therapeutic use*
  • Nerve Tissue Proteins
  • Parkinsonian Disorders* / diagnosis
  • Parkinsonian Disorders* / drug therapy
  • Parkinsonian Disorders* / genetics
  • Phenotype
  • Proteins / genetics*
  • Spinocerebellar Ataxias / diagnosis*
  • Spinocerebellar Ataxias / genetics*
  • Trinucleotide Repeat Expansion / genetics

Substances

  • Antiparkinson Agents
  • Ataxins
  • Nerve Tissue Proteins
  • Proteins
  • Levodopa