Abstract
The metabolism of oral glucurolactone to serum D-glucarate by the hepatic cytochrome P450 enzyme system was no different in 20 untreated Parkinson's disease (PD) patients as compared with 20 age- and sex-matched controls. There was no evidence for a deficit in hepatic enzymes in PD.
MeSH terms
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Administration, Oral
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Aged
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Cytochrome P-450 Enzyme System / metabolism
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Female
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Glucaric Acid / blood*
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Glucuronates / administration & dosage
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Glucuronates / metabolism*
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Humans
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Liver / enzymology
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Male
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Parkinson Disease / metabolism*
Substances
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Glucuronates
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glucuronolactone
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Cytochrome P-450 Enzyme System
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Glucaric Acid