Usefulness of the third heart sound in predicting an elevated level of B-type natriuretic peptide

Gregory M Marcus; Andrew D Michaels; Teresa De Marco; Charles E McCulloch; Kanu Chatterjee

doi:10.1016/j.amjcard.2004.01.074

Usefulness of the third heart sound in predicting an elevated level of B-type natriuretic peptide

Am J Cardiol. 2004 May 15;93(10):1312-3. doi: 10.1016/j.amjcard.2004.01.074.

Authors

Gregory M Marcus¹, Andrew D Michaels, Teresa De Marco, Charles E McCulloch, Kanu Chatterjee

Affiliation

¹ Department of Cardiology, University of California-San Francisco, M1180D, 505 Parnassus Avenue, San Francisco, CA 94143-0124, USA. [email protected]

PMID: 15135714
DOI: 10.1016/j.amjcard.2004.01.074

Abstract

Third heart sounds were sought in 100 consecutive outpatients who had B-type natriuretic peptide (BNP) levels measured within 8 hours. Mean BNP levels were significantly higher in those with a third heart sound. The presence of a third heart sound was 41% sensitive and 97% specific for elevated BNP levels.

Publication types

Evaluation Study

MeSH terms

Aged
Auscultation / methods*
Double-Blind Method
Female
Heart Diseases / blood*
Heart Diseases / diagnosis*
Humans
Male
Natriuretic Peptide, Brain / blood*
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity

Substances

Natriuretic Peptide, Brain