Abstract
Four carbapenem-resistant Pseudomonas spp. were isolated from patients in Singapore. One Pseudomonas putida isolate contained a bla(IMP-1) identical to that first described in Japan. The sequence of a variant bla(IMP-1) in Pseudomonas fluorescens contained four silent mutations compared with the original sequence. The remaining P. putida isolates contained bla(VIM-6), a novel VIM gene variant.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Blotting, Southern
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Conjugation, Genetic
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DNA, Bacterial / genetics
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Drug Resistance, Bacterial
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Isoelectric Focusing
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Molecular Sequence Data
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Plasmids / genetics
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Pseudomonas Infections / microbiology
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Pseudomonas fluorescens / drug effects
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Pseudomonas fluorescens / enzymology*
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Pseudomonas putida / drug effects
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Pseudomonas putida / enzymology*
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Reverse Transcriptase Polymerase Chain Reaction
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Singapore
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beta-Lactamases / metabolism*
Substances
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DNA, Bacterial
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beta-lactamase IMP-1
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beta-Lactamases
Associated data
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GENBANK/AY165025
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GENBANK/AY250709
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GENBANK/AY251052