Three new oxetane-ring-containing taxoids from Taxus chinensis

J Nat Prod. 2004 May;67(5):905-7. doi: 10.1021/np034042n.

Abstract

Three new 14beta-benzoyloxy taxoids containing an oxetane ring, namely, 14beta-benzoyloxybaccatin IV (1), 14beta-benzoyloxy-13-deacetylbaccatin IV (2), and 14beta-benzoyloxy-2-deacetylbaccatin VI (3), have been isolated from the leaves and stems of Taxus chinensis. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopic data.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclization
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Ethers, Cyclic / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Leaves / chemistry
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Taxoids / chemistry
  • Taxoids / isolation & purification*
  • Taxus / chemistry*

Substances

  • 14beta-benzoyloxy-13-deacetylbaccatin IV
  • 14beta-benzoyloxy-2-deacetylbaccatin VI
  • 14beta-benzoyloxybaccatin IV
  • Drugs, Chinese Herbal
  • Ethers, Cyclic
  • Taxoids
  • oxetane