Laser spectral characterization in multiphoton microscopy

Appl Opt. 2004 May 20;43(15):3055-60. doi: 10.1364/ao.43.003055.

Abstract

Spectral and temporal characterization is a fundamental task when a tunable Ti:sapphire ultrafast laser system is operated for multiphoton microscopy applications. In the present paper simple procedures are reported that perform laser-peak-emission wavelength and bandwidth measurements without the need of any further instrumentation but a simple and inexpensive diffraction grating, by taking advantage of the confocal microscope imaging capabilities.

Publication types

  • Comparative Study
  • Evaluation Study
  • Validation Study

MeSH terms

  • Equipment Design
  • Equipment Failure Analysis
  • Image Enhancement / instrumentation*
  • Image Enhancement / methods*
  • Microscopy, Confocal / instrumentation*
  • Microscopy, Confocal / methods*
  • Microscopy, Fluorescence, Multiphoton / instrumentation*
  • Microscopy, Fluorescence, Multiphoton / methods*
  • Refractometry / instrumentation*
  • Refractometry / statistics & numerical data*
  • Reproducibility of Results
  • Sensitivity and Specificity