Chemical investigation of the metabolites from the Canadian tuckahoe, Polyporus tuberaster

J Nat Prod. 1992 May;55(5):649-53. doi: 10.1021/np50083a015.

Abstract

The metabolites of the Canadian tuckahoe, the sclerotium of Polyporus tuberaster, have been investigated. The ten-membered lactone tuckolide [1] was isolated, and its structure was determined by spectroscopic methods and confirmed by X-ray crystallography. Ergosterol, ergosterol peroxide, and several unidentified ergosterol derivatives were also obtained, along with an unidentified disaccharide.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Fungi / drug effects
  • Insecta / drug effects
  • Lactones / chemistry
  • Lactones / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Polyporaceae / chemistry*
  • X-Ray Diffraction

Substances

  • Lactones
  • decarestrictine D