Outbreak of infection with hepatitis A virus (HAV) associated with a foodhandler and confirmed by sequence analysis reveals a new HAV genotype IB variant

J Clin Microbiol. 2004 Jun;42(6):2825-8. doi: 10.1128/JCM.42.6.2825-2828.2004.

Abstract

An outbreak of infection with hepatitis A virus associated with a foodhandler and involving 26 subjects occurred in Southern Italy. Sequence analysis of the VP3-VP1 and VP1-P2A junctions confirmed that the outbreak was due to a point source and allowed the identification of a new genotype IB variant. This report confirms the usefulness of sequence-based molecular fingerprinting during outbreaks.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Case-Control Studies
  • Disease Outbreaks*
  • Food Handling*
  • Genotype
  • Hepatitis A / epidemiology*
  • Hepatitis A / etiology
  • Hepatitis A / virology
  • Hepatitis A virus / classification*
  • Hepatitis A virus / genetics
  • Humans
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Analysis, DNA

Associated data

  • GENBANK/AY294046
  • GENBANK/AY294047
  • GENBANK/AY294048
  • GENBANK/AY294049