Renal failure as a determinant of mortality after cardiac transplantation

Transplant Proc. 2004 May;36(4):989-90. doi: 10.1016/j.transproceed.2004.03.109.

Abstract

Introduction: Patients with heart failure frequently develop renal failure, which increases the mortality rate among patients undergoing cardiac transplantation.

Purpose: To determine whether preoperative renal function influenced postoperative mortality in cardiac transplantation recipients.

Materials and methods: The measurements of plasma urea, plasma creatinine, and 24-hour creatinine clearance in patients who underwent cardiac transplantation were correlated with mortality at 30, 90, and 365 days after the procedure, using Student t test for continuous variables and the chi-square test for categorical variables.

Results: All variables correlated with mortality, particularly plasma creatinine at 30, 90, and 365 days (P =.029,.003, and.0029, respectively).

Conclusion: Preoperative renal failure is a mortality indicator in cardiac transplantation recipients.

MeSH terms

  • Female
  • Heart Transplantation / mortality*
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / classification
  • Postoperative Complications / mortality
  • Renal Insufficiency / epidemiology*
  • Renal Insufficiency / mortality
  • Retrospective Studies