Abstract
Five Mycobacterium tuberculosis complex isolates in California were identified as M. africanum by spoligotyping, single nucleotide polymorphisms, a deletion mutation, and phenotypic traits, confirming it as a cause of tuberculosis in the United States. Three of the five patients from whom M. africanum was isolated had lived in Africa.
MeSH terms
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Adult
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Africa
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Bacterial Typing Techniques
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California
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DNA, Bacterial / analysis
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DNA, Bacterial / genetics
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Female
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Gene Deletion
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Genotype
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Humans
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Male
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Mycobacterium / classification*
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Mycobacterium / genetics
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Mycobacterium / isolation & purification*
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Oligonucleotides / genetics
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Phenotype
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Polymorphism, Single Nucleotide
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Tuberculosis, Pulmonary / microbiology*
Substances
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DNA, Bacterial
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Oligonucleotides